CD36 Monoclonal / PE / REA760

Citations: (3)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-110-877 (View supplier product page)
Size 30 tests in 60 µL
Price $110.00
Antigen CD36
Clone REA760
Host Human
Isotype IgG1
Conjugate PE
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
Description Clone REA760 recognizes the human CD36 antigen, an integral membrane protein, which is a member of the class B scavenger receptor family of cell surface proteins. CD36 is expressed on various epithelial and endothelial cells as well as erythrocytes, platelets, monocytes, and macrophages, and some macrophage-derived dendritic cells. CD36 functions as a scavenger receptor for long chain fatty acids, oxidized LDL, collagen type I, IV, and V, and thrombospondin, as well as for apoptotic cells. CD36 is an early marker of erythroid differentiation. | Additional information: Clone REA760 displays negligible binding to Fc receptors.
About CD36 and PE
CD36 The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Citations
Reviews & Ratings
PE Excitation and Emission Spectra