CLEC4D Monoclonal / APC-Vio770 / REA757

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-110-861 (View supplier product page)
Size 30 tests in 60 µL
Price $155.00
Antigen CLEC4D
Clone REA757
Host Human
Isotype IgG1
Conjugate APC-Vio770
Target Species Human
Applications FC
Description Clone REA757 recognizes the human CLEC4D antigen, a cell-surface receptor that belongs to the human calcium-dependent lectin family (C-type lectin), also known as CLECSF8, CLEC-6, or MCL. CLEC4D is expressed in a low level in peripheral blood leukocytes, in bone marrow, and spleen. It is mainly found in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-α, and IFN-γ. | Additional information: Clone REA757 displays negligible binding to Fc receptors.
About CLEC4D and APC-Vio770
CLEC4D This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
APC-Vio770 APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
Citations
PMID 14971047
PMID 15368084
Additional
Sources
Reviews & Ratings
APC-Vio770 Excitation and Emission Spectra