CLEC4D Monoclonal / APC-Vio770 / REA757
CLEC4D Monoclonal / APC-Vio770 / REA757
Citations:
(2)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-110-861 (View supplier product page) | |
Size | 30 tests in 60 µL | |
Price | $155.00 | |
Antigen | CLEC4D | |
Clone | REA757 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | APC-Vio770 | |
Target Species | Human | |
Applications | FC | |
Description | Clone REA757 recognizes the human CLEC4D antigen, a cell-surface receptor that belongs to the human calcium-dependent lectin family (C-type lectin), also known as CLECSF8, CLEC-6, or MCL. CLEC4D is expressed in a low level in peripheral blood leukocytes, in bone marrow, and spleen. It is mainly found in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-α, and IFN-γ. | Additional information: Clone REA757 displays negligible binding to Fc receptors. |
About CLEC4D and APC-Vio770
CLEC4D | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] | |
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APC-Vio770 | APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry. |
Citations
PMID 14971047 | ||
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PMID 15368084 | ||
Additional Sources |
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Reviews & Ratings
APC-Vio770 Excitation and Emission Spectra
$155.00
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