CD102 Monoclonal / APC / REA745
CD102 Monoclonal / APC / REA745
Citations:
(1)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-112-030 (View supplier product page) | |
Size | 30 µg in 200 µL | |
Price | $90.00 | |
Antigen | CD102 | |
Clone | REA745 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | APC | |
Target Species | Mouse | |
Applications | FC | |
Description | Clone REA745 recognizes the mouse CD102 antigen, also known as intercellular adhesion molecule 2 (ICAM-2). CD102 is a type I transmembrane glycoprotein belonging to the ICAM proteins of the Ig superfamily. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1. CD102 is found in endothelial cells and leukocytes and is expressed in high level in lung. CD102 plays a role in adhesive interactions, which are important for antigen-specific immune response, in NK-cell mediated clearance, and lymphocyte recirculation. Furthermore, CD102 is involved in other cellular interactions which are important for immune response and surveillance. | Additional information: Clone REA745 displays negligible binding to Fc receptors. |
About CD102 and APC
CD102 | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] | |
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APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
PMID 1401904 | ||
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PMID 7553659 | ||
PMID 10077629 | ||
Additional Sources |
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Reviews & Ratings
APC Excitation and Emission Spectra
$90.00
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