CD326 Monoclonal / APC / REA764

Citations: (2)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-111-117 (View supplier product page)
Size 30 tests in 60 µL
Price $150.00
Antigen CD326
Clone REA764
Host Human
Isotype IgG1
Conjugate APC
Target Species Human
Applications MICS (MACSima Imaging Cyclic Staining), FC, IF, IHC, 3D-IF
Description Clone REA764 recognizes CD326, also known as human epithelial antigen (HEA), epithelial cell adhesion molecule (EpCAM), or epithelial-specific antigen (ESA), and is involved in cell adhesion. The CD326 antigen is broadly expressed on the basolateral surface of carcinoma and epithelial cells in tissues or on circulating tumor cells and cancer stem cells, but is not found on melanoma, neuroblastoma, sarcoma, lymphoma, leukemia cells, or normal fibroblasts. Furthermore, it is suggested, that CD326 could be used as a surface marker for human ESCs. | Additional information: Clone REA764 displays negligible binding to Fc receptors.
About CD326 and APC
CD326 This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Citations
Reviews & Ratings
APC Excitation and Emission Spectra