MED12 / DyLight 405 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-2357V (View supplier product page)
Size 100 ul
Price $549.00
Antigen MED12
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 405
Target Species Human, Mouse, Primate
Applications WB, ICC/IF, IHC-P, IHC
Description Rabbit MED12 antibody reacts with Human, Mouse, Primate [DyLight 405]
About MED12 and DyLight 405
MED12 The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

DyLight 405 Excitation and Emission Spectra