mTOR / DyLight 650 /
mTOR / DyLight 650 /
Product Details
| Supplier | Novus Biologicals, a Bio-Techne brand | |
|---|---|---|
| Catalog #: | NB100-240C (View supplier product page) | |
| Size | 100 ul | |
| Price | $549.00 | |
| Antigen | mTOR | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | DyLight 650 | |
| Target Species | Human, Rat | |
| Applications | WB, ICC/IF, IHC | |
| Description | Rabbit TOR/mTOR antibody reacts with Human, Rat [DyLight 650] |
About mTOR and DyLight 650
| mTOR | The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Inhibitors of mTOR are used in organ transplants as immunosuppressants, and are being evaluated for their therapeutic potential in SARS-CoV-2 infections. Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Aug 2020] | |
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| DyLight 650 | DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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Reviews & Ratings
DyLight 650 Excitation and Emission Spectra
$549.00
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