S100B Monoclonal / DyLight 650 / 4C4.9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54579C (View supplier product page)
Size 100 μl
Price $429.00
Antigen S100B
Clone 4C4.9
Host Mouse
Isotype IgG2a κ
Conjugate DyLight 650
Target Species Bovine, Human, Mouse, Rat
Applications WB, FC, ICC/IF, IHC-P, IHC
Description Mouse S100B antibody [DyLight 650] detects Human, Mouse, Rat, Bovine
About S100B and DyLight 650
S100B The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
DyLight 650 DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 650 Excitation and Emission Spectra