gamma H2AX DyLight 488 (Rabbit) - Reactivity: Canine, Human, Mouse, Rat

Product Details
Description Histone H2AX [p Ser139] Antibody [DyLight 488]
Conjugate DyLight 488
Clone
Target Species Canine, Human, Mouse, Rat
Applications ICC, FC, IHC, ChIP, IF
Supplier Novus Biologicals, a Bio-Techne brand
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About gamma H2AX
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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$669.00