p53 / DyLight 755 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB200-171IR (View supplier product page)
Size 100 ul
Price $559.00
Antigen p53
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 755
Target Species Human
Applications WB, FC, ICC/IF, IHC-P, IHC, KD
Description Rabbit p53 antibody [DyLight 755] detects Human
About p53 and DyLight 755
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra