RB1 / DyLight 550 / Rb1 (1F8)

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50271R (View supplier product page)
Size 100 μl
Price $379.00
Antigen RB1
Clone Rb1 (1F8)
Host Mouse
Isotype IgG1
Conjugate DyLight 550
Target Species Human
Applications ICC/IF, IHC
Description Mouse RB1 antibody [DyLight 550] reacts with Human
About RB1 and DyLight 550
RB1 The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra