Adiponectin / DyLight 550 / ADPN/1370

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54319R (View supplier product page)
Size 100 ul
Price $519.00
Antigen Adiponectin
Clone ADPN/1370
Host Mouse
Isotype IgG2b
Conjugate DyLight 550
Target Species Human
Applications FC, ICC/IF, IHC-P, IHC
Description This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.
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DyLight 550 Excitation and Emission Spectra