IFN-alpha 2 / DyLight 755 / N27

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54409IR (View supplier product page)
Size 100 μl
Price $429.00
Antigen IFN-alpha 2
Clone N27
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 755
Target Species Human
Applications FC, ICC/IF
Description Mouse IFN-alpha 2 antibody [DyLight 755] detects Human
About IFN-alpha 2 and DyLight 755
IFN-alpha 2 This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach. [provided by RefSeq, Aug 2020]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra