IFN-alpha 2 / DyLight 650 / N27

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54409C (View supplier product page)
Size 100 μl
Price $429.00
Antigen IFN-alpha 2
Clone N27
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 650
Target Species Human
Applications FC, ICC/IF
Description Mouse IFN-alpha 2 antibody [DyLight 650] detects Human
About IFN-alpha 2 and DyLight 650
IFN-alpha 2 This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach. [provided by RefSeq, Aug 2020]
DyLight 650 DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 650 Excitation and Emission Spectra