MUC-1 / Brilliant Ultraviolet 395 / HMPV
MUC-1 / Brilliant Ultraviolet 395 / HMPV
Product Details
| Supplier | BD Biosciences | |
|---|---|---|
| Catalog #: | 743411 (View supplier product page) | |
| Size | 50 μg | |
| Price | $538.00 | |
| Antigen | MUC-1 | |
| Clone | HMPV | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | Brilliant Ultraviolet 395 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Hu MUC1 (CD227) BUV395 HMPV 50ug |
About MUC-1 and Brilliant Ultraviolet 395
| MUC-1 | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011] | |
|---|---|---|
| Brilliant Ultraviolet 395 | Brilliant™ UltraViolet 395 (BUV395) is a UV-emitting base polymer dye that can be excited by the 355 nm UV laser and collected using a 379/28 bandpass filter. BUV395 has an excitation peak at 348 nm and an emission peak at 395. BUV395's fairly unique excitation and emission spectrum causes relatively little spillover into other common detectors and conflicts with very few other commonly used fluorophores. An alternative to BUV395 for flow cytometry is StarBright UltraViolet 400. This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. These dyes were optimized for use with multicolor flow cytometry. BUV395 forms the backbone of the family, as all other members are tandems that use it as the acceptor, thus making them excitable by the same 355 nm UV laser. |
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Brilliant Ultraviolet 395 Excitation and Emission Spectra
$538.00
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