FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-110-506 (View supplier product page)
	Size	100 tests in 200 µL
	Price	$365.00
	Antigen	CD83
	Clone	REA714
	Host	Human
	Isotype	IgG1
	Conjugate	APC-Vio770
	Target Species	Human
	Applications	FC
	Description	Clone REA714 recognizes the human CD83 antigen, a 45 kDa glycoprotein member of the immunoglobulin superfamily of receptors. In humans, CD83 is expressed on the surface of activated dendritic cells (DCs) and can therefore be used as a marker for the phenotypical characterization of DC maturation. CD83 plays a role in antigen presentation and lymphocyte activation. \| Additional information: Clone REA714 displays negligible binding to Fc receptors.

	CD83	The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
	APC-Vio770	APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

$365.00
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CD83 Monoclonal / APC-Vio770 / REA714