CD83 Monoclonal / APC / REA714
CD83 Monoclonal / APC / REA714
Citations:
(3)
Product Details
Supplier | Miltenyi Biotec | |
---|---|---|
Catalog #: | 130-110-504 (View supplier product page) | |
Size | 100 tests in 200 µL | |
Price | $325.00 | |
Antigen | CD83 | |
Clone | REA714 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | APC | |
Target Species | Human | |
Applications | FC | |
Description | Clone REA714 recognizes the human CD83 antigen, a 45 kDa glycoprotein member of the immunoglobulin superfamily of receptors. In humans, CD83 is expressed on the surface of activated dendritic cells (DCs) and can therefore be used as a marker for the phenotypical characterization of DC maturation. CD83 plays a role in antigen presentation and lymphocyte activation. | Additional information: Clone REA714 displays negligible binding to Fc receptors. |
About CD83 and APC
CD83 | The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] | |
---|---|---|
APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
PMID 1378080 | ||
---|---|---|
PMID 7706722 | ||
PMID 8145033 | ||
PMID 12072358 | ||
PMID 15320871 | ||
Additional Sources |
Reviews & Ratings
APC Excitation and Emission Spectra
$325.00
Supplier Page
Supplier Page