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	Supplier	Miltenyi Biotec
	Catalog #:	130-110-812 (View supplier product page)
	Size	30 tests in 60 µL
	Price	$150.00
	Antigen	CD31
	Clone	REA730
	Host	Human
	Isotype	IgG1
	Conjugate	Vio Blue
	Target Species	Human
	Applications	FC, 3D-IF, IF, IHC, Mass Cytometry
	Description	Clone REA730 recognizes the human CD31 antigen, also known as PECAM-1. CD31 is a member of the immunoglobulin superfamily and is involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is a 120–140 kDa single-chain transmembrane glycoprotein expressed on endothelial cells, monocytes, platelets, granulocytes, and several lymphocyte subsets. During maturation of CD4+ T cells, the expression of CD31 changes: CD4+ recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture. \| Additional information: Clone REA730 displays negligible binding to Fc receptors.

	CD31	The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
	Vio Blue	Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec).

$150.00
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CD31 Monoclonal / Vio Blue / REA730