CD31 Monoclonal / PE / REA730
CD31 Monoclonal / PE / REA730
Citations:
(2)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-110-669 (View supplier product page) | |
Size | 100 tests in 200 µL | |
Price | $310.00 | |
Antigen | CD31 | |
Clone | REA730 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | PE | |
Target Species | Human | |
Applications | FC, 3D-IF, IF, IHC, Mass Cytometry | |
Description | Clone REA730 recognizes the human CD31 antigen, also known as PECAM-1. CD31 is a member of the immunoglobulin superfamily and is involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is a 120–140 kDa single-chain transmembrane glycoprotein expressed on endothelial cells, monocytes, platelets, granulocytes, and several lymphocyte subsets. During maturation of CD4+ T cells, the expression of CD31 changes: CD4+ recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture. | Additional information: Clone REA730 displays negligible binding to Fc receptors. |
About CD31 and PE
CD31 | The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010] | |
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PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Citations
PMID 1690453 | ||
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PMID 1700999 | ||
PMID 11901204 | ||
Additional Sources |
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Reviews & Ratings
PE Excitation and Emission Spectra
$310.00
Supplier Page
Supplier Page