Glycophorin C / DyLight 680 / BRIC4

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-33304FR (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Glycophorin C
Clone BRIC4
Host Mouse
Isotype IgG1
Conjugate DyLight 680
Target Species Human
Applications WB, FC, IHC-Fr, IHC
Description NBP2-33304 recognises the erythrocyte transmembrane glycoprotein CD236, also known as glycophorin C (GPC). CD236 is an integral membrane protein which carries the Gerbich blood group antigens. Expression of CD236 is not restricted to erythroid cells, but is broadly distributed in both erythroid and non-erythroid tissues. Clone BRIC4 specifically reacts with an epitope located within residues 2-21 of CD236.
About Glycophorin C and DyLight 680
Glycophorin C Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra