Alkaline Phosphatase / DyLight 405 / H7E8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB500-532V (View supplier product page)
Size 0.1 ml
Price $469.00
Antigen Alkaline Phosphatase
Clone H7E8
Host Mouse
Isotype IgG2a
Conjugate DyLight 405
Target Species Human
Applications IHC-P, WB, ELISA, IHC-Fr, IHC
Description The antibody H7E8 recognizes throphoblast-derived membrane-associated enzyme alkaline phosphatase.
About Alkaline Phosphatase and DyLight 405
Alkaline Phosphatase This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra