CD16 Monoclonal / APC-Cy7 / 3G8

Product Details
Supplier EXBIO
Catalog #: T4-646-T025 (View supplier product page)
Size 25 Tests
Price $125.00
Antigen CD16
Clone 3G8
Host Mouse
Isotype IgG1 κ
Conjugate APC-Cy7
Target Species Human, Non-Human Primate
Applications FC, IP, IHC-Fr
Description CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms – FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-beta subunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
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APC-Cy7 Excitation and Emission Spectra