CD28 Monoclonal / APC / CD28.2

Product Details
Supplier EXBIO
Catalog #: 1A-577-T100 (View supplier product page)
Size 100 Tests
Price $220.00
Antigen CD28
Clone CD28.2
Host Mouse
Isotype IgG1 κ
Conjugate APC
Target Species Human, Non-Human Primate
Applications FC, IP, WB, IHC-Fr, ICC
Description CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
About CD28 and APC
CD28 The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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APC Excitation and Emission Spectra