NTAL Polyclonal / Unconjugated / PAb (486)

Product Details
Supplier EXBIO
Catalog #: 11-486-C100 (View supplier product page)
Size 100 μg
Price $180.00
Antigen NTAL
Clone PAb (486)
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Mouse
Applications WB
Description NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
About NTAL and Purified
NTAL This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra