CD45RB Monoclonal / Alexa Fluor 700 / MEM-55

Product Details
Supplier EXBIO
Catalog #: A7-224-T100 (View supplier product page)
Size 100 Tests
Price $220.00
Antigen CD45RB
Clone MEM-55
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 700
Target Species Human, Non-Human Primate
Applications FC, IP, WB, IHC-P
Description CD45RB is an of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed e.g. in microglia and inflammatory cells.
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Alexa Fluor 700 Excitation and Emission Spectra