CD16 Monoclonal / FITC / MEM-154

Product Details
Supplier EXBIO
Catalog #: 1F-214-T100 (View supplier product page)
Size 100 Tests
Price $180.00
Antigen CD16
Clone MEM-154
Host Mouse
Isotype IgG1
Conjugate FITC
Target Species Human
Applications FC, IP, WB, Functional
Description CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms – FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-beta subunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
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FITC Excitation and Emission Spectra