GAPDH / DyLight 750 / 6C5

Citations: (10)
Product Details
Supplier Bio-Rad
Catalog #: MCA4739D750 (View supplier product page)
Size 100 μg
Price $273.00
Antigen GAPDH
Clone 6C5
Host Mouse
Isotype IgG1
Conjugate DyLight 750
Target Species Rabbit
Applications WB
Description MOUSE ANTI RABBIT GAPDH:DyLight®750
About GAPDH and DyLight 750
GAPDH This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
DyLight 750 DyLight™ 750 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 750 and Cy7.
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DyLight 750 Excitation and Emission Spectra