HEXA / DyLight 755 / 20F1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-42629IR (View supplier product page)
Size 100 ul
Price $499.00
Antigen HEXA
Clone 20F1
Host Mouse
Isotype IgG2a λ
Conjugate DyLight 755
Target Species Human
Applications WB, ELISA, FC
About HEXA and DyLight 755
HEXA This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra