HAX-1 / DyLight 405 / 3C5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-30169V (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen HAX-1
Clone 3C5
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 405
Target Species Human
Applications WB, ELISA, ICC/IF
Description HAX-1 Antibody (3C5) [DyLight 405]
About HAX-1 and DyLight 405
HAX-1 The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra