HAX-1 / DyLight 350 / 3C5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-30169UV (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen HAX-1
Clone 3C5
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 350
Target Species Human
Applications WB, ELISA, ICC/IF
Description HAX-1 Antibody (3C5) [DyLight 350]
About HAX-1 and DyLight 350
HAX-1 The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra