CD134 / PerCP / OX-86

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64847PCP (View supplier product page)
Size 0.125 ml
Price $449.00
Antigen CD134
Clone OX-86
Host Rat
Isotype IgG1
Conjugate PerCP
Target Species Mouse
Applications FC, IHC-Fr, IHC
Description NB100-64847 recognises murine OX40 (CD134), a cell surface antigen expressed only by activated T lymphocytes.
About CD134 and PerCP
CD134 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
PerCP Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer.
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PerCP Excitation and Emission Spectra