EDAR / DyLight 488 / ED5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64609G (View supplier product page)
Size 125 μl
Price $399.00
Antigen EDAR
Clone ED5
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Mouse (Negative), Rat
Applications IHC-Fr, IHC
Description ED5 staining reveals a web-like pattern in B cell follicles, representing the follicular dendritic cells. Mesangial cells in the kidney are also ED5-positive.
About EDAR and DyLight 488
EDAR This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra