EDAR / Alexa Fluor 488 / ED5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64609AF488 (View supplier product page)
Size 125 μl
Price $399.00
Antigen EDAR
Clone ED5
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 488
Target Species Mouse (Negative), Rat
Applications IHC-Fr, IHC
Description ED5 staining reveals a web-like pattern in B cell follicles, representing the follicular dendritic cells. Mesangial cells in the kidney are also ED5-positive.
About EDAR and Alexa Fluor 488
EDAR This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Alexa Fluor 488 Excitation and Emission Spectra