CD44 / Alexa Fluor 488 / Hermes-1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-22530AF488 (View supplier product page)
Size 0.2 ml
Price $559.00
Antigen CD44
Clone Hermes-1
Host Rat
Isotype IgG2a
Conjugate Alexa Fluor 488
Target Species Bovine, Goat, Human, Mouse, Rabbit, Sheep
Applications ICC/IF, WB, ELISA, FC, IHC
Description Rat CD44 antibody [Alexa Fluor 488] reacts with Human, Mouse, Bovine, Goat, Rabbit, Sheep
About CD44 and Alexa Fluor 488
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
Images
  CD44 Alexa Fluor 488 Novus Biologicals, a Bio-Techne brand antibody anti target:Bovine, Goat, Human, Mouse, Rabbit, Sheep host:Rat isotype:IgG2a clone:Hermes-1 Flow Cytometry: CD44 Antibody (Hermes-1) [Alexa Fluor® 488] [NBP2-22530AF488] - A surface stain w...

Flow Cytometry: CD44 Antibody (Hermes-1) [Alexa Fluor® 488] [NBP2-22530AF488] - A surface stain was performed on U-87 cells with CD44 [Hermes-1] Antibody NBP2-22530AF488 (blue) and a matched isotype control (orange). Cells were incubated in an antibody dilution of 5 ug/mL for 20 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 488.

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Alexa Fluor 488 Excitation and Emission Spectra