CD247 / DyLight 488 / EM-54

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-37708G (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen CD247
Clone EM-54
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Human, Mouse
Applications WB, ICFC
Description Antibody recognizes phosphorylated tyrosine 142 of CD3 zeta chain (CD247), which is a component of TCR/CD3 complex expressed on T cells.
About CD247 and DyLight 488
CD247 The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra