APITD1 Polyclonal / Unconjugated /
APITD1 Polyclonal / Unconjugated /
Citations:
(1)
Product Details
| Supplier | Thermo Fisher Scientific | |
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| Catalog #: | PA5-24846 (View supplier product page) | |
| Size | 400 μl | |
| Price | $456.00 | |
| Antigen | APITD1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | WB, FC, IHC-P | |
| Description | APITD1 Polyclonal Antibody |
About APITD1 and Purified
| APITD1 | This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2010] |
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Images
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Flow cytometry analysis of Jurkat cells using an APITD1 polyclonal antibody (Product # PA5-24846) (right) compared to a negative control cell (left) at a dilution of 1:10-50, followed by a FITC-conjugated goat anti-rabbit antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$456.00
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