AMPK alpha 2 / Unconjugated /
AMPK alpha 2 / Unconjugated /
Product Details
| Supplier | Thermo Fisher Scientific | |
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| Catalog #: | PA5-25987 (View supplier product page) | |
| Size | 400 μl | |
| Price | $330.00 | |
| Antigen | AMPK alpha 2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, FC | |
| Description | AMPK alpha-2 Polyclonal Antibody |
About AMPK alpha 2 and Purified
| AMPK alpha 2 | The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008] |
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Images
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Flow cytometry analysis of K562 cells using a PRKAA2 polyclonal antibody (Product # PA5-25987) (right) compared to a negative control cell (left) at a dilution of 1:10-50, followed by a FITC-conjugated goat anti-rabbit antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$330.00
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