CD8a Monoclonal / Biotin / OX-8
CD8a Monoclonal / Biotin / OX-8
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | MA5-17395 (View supplier product page) | |
| Size | 100 μg | |
| Price | $233.00 | |
| Antigen | CD8a | |
| Clone | OX-8 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Biotin | |
| Target Species | Rat | |
| Applications | WB, FC, IHC-P, IHC | |
| Description | CD8 alpha Monoclonal Antibody (OX-8), Biotin |
About CD8a and Biotin
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] |
|---|
Images
|
Flow cytometric analysis of Wistar rat splenocytes (left) or thymocytes (right) were stained using a CD8a/T subset NK monoclonal antibody (Product # MA5-17395) (filled histogram) or mouse IgG1, Kappa isotype control (open histogram). |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Biotin Excitation and Emission Spectra
$233.00
Supplier Page
Supplier Page
