CD38 / PE-Cy5 / HIT2

Citations: (2)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: MA5-16705 (View supplier product page)
Size 100 Tests
Price $449.00
Antigen CD38
Clone HIT2
Host Mouse
Isotype IgG1
Conjugate PE-Cy5
Target Species Human
Applications FC
Description CD38 Monoclonal Antibody (HIT2), PE-Cyanine5
About CD38 and PE-Cy5
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
PE-Cy5 PE-Cyanine®5 (PE-Cy5) is a red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy5. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy5. PE-Cy5 has an excitation peak at 496 nm and an emission peak at 667 nm.
Citations
PMID 10627452
PMID 15627612
Additional
Sources
Reviews & Ratings
PE-Cy5 Excitation and Emission Spectra