FluoroFinder

	Supplier	Thermo Fisher Scientific
	Catalog #:	MA5-17966 (View supplier product page)
	Size	100 μg
	Price	$269.00
	Antigen	CD160
	Clone	CNX46-3
	Host	Rat
	Isotype	IgG2b
	Conjugate	Biotin
	Target Species	Mouse
	Applications	WB, FC
	Description	CD160 Monoclonal Antibody (CNX46-3), Biotin

	CD160	CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]

		Flow cytometric analysis of C3H/HE intestinal intraepithelial lymphocytes stained using a CD160/BY55 antigen monoclonal antibody (Product # MA5-17966) (filled histogram) or mouse IgG2b, kappa isotype control (open histogram).
		Flow cytometric analysis of Intestinal Intraepithelial Lymphocytes staining using anti-CD160/BY55 antigen Monoclonal Antibody (Product # MA5-17966) at a 1.0 µg/10^6 cells dilution.