ATP7b / Unconjugated / CC15

Citations: (1)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: MA5-16616 (View supplier product page)
Size 250 μg
Price $449.00
Antigen ATP7b
Clone CC15
Host Mouse
Isotype IgG2a
Conjugate Unconjugated
Target Species Bovine, Goat, Sheep
Applications IP, FC, IHC-Fr, IHC-P
Description WC1 Monoclonal Antibody (CC15)
About ATP7b and Purified
ATP7b This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra