CD104 Monoclonal / Unconjugated / 450-9D

Citations: (2)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: MA1-80984 (View supplier product page)
Size 200 μg
Price $470.00
Antigen CD104
Clone 450-9D
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human, Mustelid
Applications WB, FC, IP, IHC
Description CD104 Monoclonal Antibody (450-9D)
About CD104 and Purified
CD104 Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Citations
PMID 24511464
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Purified Excitation and Emission Spectra