IL-10 R alpha / Biotin / 3F9

Product Details
Supplier Thermo Fisher Scientific
Catalog #: MA1-36187 (View supplier product page)
Size 100 μg
Price $700.00
Antigen IL-10 R alpha
Clone 3F9
Host Rat
Isotype IgG2a
Conjugate Biotin
Target Species Human
Applications FC
Description IL10RA Monoclonal Antibody (3F9), Biotin
About IL-10 R alpha and Biotin
IL-10 R alpha The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
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Biotin Excitation and Emission Spectra