IL-6 Monoclonal / PE / 1936
IL-6 Monoclonal / PE / 1936
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | MA5-23545 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $327.00 | |
| Antigen | IL-6 | |
| Clone | 1936 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | PE | |
| Target Species | Human | |
| Applications | FC | |
| Description | IL-6 Monoclonal Antibody (1936), PE |
About IL-6 and PE
| IL-6 | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Images
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Flow cytometric analysis of human peripheral blood mononuclear cells (PBMCs) treated with LPS were stained with mouse Anti-human IL-6 PE-conjugated Monoclonal Antibody (Product # MA5-23545) or isotype control antibodyopen histogram. To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I. |
Citations
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Reviews & Ratings
PE Excitation and Emission Spectra
$327.00
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