FluoroFinder

	Supplier	BioLegend
	Catalog #:	808501 (View supplier product page)
	Size	200UL
	Price	$390.00
	Antigen	Parkin
	Clone	Prk 8
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	Unconjugated
	Target Species	Human, Mouse, Rat
	Applications	WB, ICC, IHC-P
	Description	Purified (azide-free) anti-Parkin

	Parkin	The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]

		Western blot of purified anti-Parkin antibody (clone Prk 8). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain lysate; Lane 3: 20 µg of mouse brain lysate; Lane 4: 20 µg of rat brain lysate. The blot was incubated with 1 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
		Western blot of purified anti-Parkin antibody (clone Prk 8). Lane 1: Molecular weight marker; Lane 2: 20 µg of mouse skeletal muscle lysate. The blot was incubated with 1 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.