LONP1 / Alexa Fluor 647 / LON20/H1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50478AF647 (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen LONP1
Clone LON20/H1
Host Mouse
Isotype IgG
Conjugate Alexa Fluor 647
Target Species Human
Applications WB, ELISA, IHC, KD
Description Mouse LONP1 antibody [Alexa Fluor 647] reacts with Human
About LONP1 and Alexa Fluor 647
LONP1 This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra