Spastin Monoclonal / Alexa Fluor 647 / Sp 6C6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50303AF647 (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen Spastin
Clone Sp 6C6
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 647
Target Species Human, Mouse, Rat
Applications WB, ELISA
Description Mouse Spastin antibody [Alexa Fluor 647] reacts with Human, Mouse, Rat
About Spastin and Alexa Fluor 647
Spastin This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The use of alternative translational initiation sites in this gene results in a single transcript variant that can produce isoforms that differ in the length of their N-terminus and which thereby differ in the efficiency of their export from the nucleus to the cytoplasm. In addition, alternative splicing results in multiple transcript variants that encode isoforms that differ in other protein regions as well. One isoform of this gene has been shown to be a microtubule-severing enzyme that regulates microtubule abundance, mobility, and plus-end distribution. Mutations in this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq, May 2018]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra