Mus81 / Alexa Fluor 647 / mta30 2g10/3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-2064AF647 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Mus81
Clone mta30 2g10/3
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 647
Target Species Human
Applications WB, IHC-P, IHC
Description Mouse Mus81 antibody reacts with Human [Alexa Fluor 647]
About Mus81 and Alexa Fluor 647
Mus81 This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks. [provided by RefSeq, Jun 2017]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra