HLA-DOB / DyLight 350 / DOB 10E6/5
HLA-DOB / DyLight 350 / DOB 10E6/5
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP2-50420UV (View supplier product page) | |
Size | 0.1 ml | |
Price | $449.00 | |
Antigen | HLA-DOB | |
Clone | DOB 10E6/5 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | DyLight 350 | |
Target Species | Human | |
Applications | WB, ELISA | |
Description | Mouse HLA DOB antibody [DyLight 350] reacts with Human |
About HLA-DOB and DyLight 350
HLA-DOB | HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008] | |
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DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
Reviews & Ratings
DyLight 350 Excitation and Emission Spectra
$449.00
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