Pappalysin-1 / DyLight 350 / 7A6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-73060UV (View supplier product page)
Size 0.2 ml
Price $469.00
Antigen Pappalysin-1
Clone 7A6
Host Mouse
Isotype IgG2a
Conjugate DyLight 350
Target Species Human
Applications WB, ELISA
Description Human PAPP-A antigen purified from placental blood (heterotetrameric complex, consisting of PAPP-A subunits and pro-MBP subunits).
About Pappalysin-1 and DyLight 350
Pappalysin-1 This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra