p53 Monoclonal / DyLight 405 / V5P4H6*B3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50231V (View supplier product page)
Size 0.1 ml
Price $459.00
Antigen p53
Clone V5P4H6*B3
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 405
Target Species Zebrafish
Applications WB, ELISA, IHC
Description Mouse p53 antibody [DyLight 405] reacts with Zebrafish
About p53 and DyLight 405
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra